Selected publications

COSTA-LOTUFO, L. V. ; CARNEVALE-NETO, F. ; TRINDADE-SILVA, A. E. ; SILVA, R. R. ; SILVA, G. G. Z. ; WILKE, D. V. ; PINTO, F. C. L. ; SAHM, B. D. B. ; JIMENEZ, P. C. ; MENDONÇA, J. N. ; LOTUFO, T. M. C. ; PESSOA, O. D. L. ; LOPES, N. P. . Chemical profiling of two congeneric sea mat corals along the Brazilian coast: adaptive and functional patterns. CHEMICAL COMMUNICATIONS, v. 00, p. 000, 2018.

UCHOA, PAULA KARINA S. ; PIMENTA, ANTONIA T. A. ; BRAZ-FILHO, RAIMUNDO ; DE OLIVEIRA, MARIA DA CONCEIÇÃO F. ; SARAIVA, NATÁLIA N. ; RODRIGUES, BARBARA S. F. ; PFENNING, LUDWIG H. ; ABREU, LUCAS M. ; Wilke, Diego V. ; FLORÊNCIO, KATHARINE G. D. ; LIMA, MARY ANNE S. . New cytotoxic furan from the marine sediment-derived fungi. Natural Product Research, v. x, p. 1-5, 2017.

AMBROSE, ANDREW J. ; SANTOS, EVELYNE A. ; JIMENEZ, PAULA C. ; ROCHA, D. D. ; WILKE, D. V. ; BEUZER, PAOLO ; AXELROD, JOSH ; KANDULURU, ANANDA KUMAR ; FUCHS, PHILIP L. ; CANG, HU ; Costa-Lotufo, Letícia V. ; CHAPMAN, ELI ; LA CLAIR, JAMES J. . Ritterostatin GN1N, a Cephalostatin-Ritterazine bis-Steroidal Pyrazine Hybrid, Selectively Targets GRP78. ChemBioChem (Print), v. -, p. -, 2017

PINTO, FRANCISCO ; ALMEIDA, JOSÉ GUSTAVO ; SILVEIRA, EDILBERTO ; COSTA, ARINICE ; GUIMARÃES, LARISSA ; WILKE, DIEGO ; COSTA-LOTUFO, LETÍCIA ; TORRES, MARIA DA CONCEIÇÃO ; PESSOA, OTÍLIA DEUSDÊNIA . Steroids from the Brazilian Zoanthids Palythoa caribaeorum and Palythoa variabilis. Journal of the Brazilian Chemical Society (Impresso), v. 28, p. 485-491, 2016.

SILVA, AMARO ; GUIMARÃES, LARISSA ; FERREIRA, ELTHON ; TORRES, MARIA DA CONCEIÇÃO ; DA SILVA, ALISON ; BRANCO, PAOLA ; OLIVEIRA, FRANCISCA ANDRÉA ; SILVA, GENIVALDO ; WILKE, DIEGO ; SILVEIRA, EDILBERTO ; PESSOA, OTÍLIA DEUSDENIA ; JIMENEZ, PAULA ; COSTA-LOTUFO, LETICIA . Bioprospecting Anticancer Compounds from the Marine-Derived Actinobacteria Actinomadura sp. Collected at the Saint Peter and Saint Paul Archipelago (Brazil). Journal of the Brazilian Chemical Society (Impresso), v. 28, p. 465-474, 2016.

SANTOS, EVELYNE A. ; QUINTELA, AMANDA L. ; FERREIRA, ELTHON G. ; SOUSA, THICIANA S. ; PINTO, FRANCISCO DAS CHAGAS L. ; HAJDU, EDUARDO ; CARVALHO, MARIANA S. ; SALANI, SULA ; ROCHA, DANILO D. ; WILKE, DIEGO V. ; TORRES, MARIA DA CONCEIÇÃO M. ; JIMENEZ, PAULA C. ; SILVEIRA, EDILBERTO R. ; LA CLAIR, JAMES J. ; PESSOA, OTÍLIA DEUSDÊNIA L. ; Costa-Lotufo, Letícia V. . Cytotoxic Plakortides from the Brazilian Marine Sponge. Journal of Natural Products (Print), v. 78, p. 996-1004, 2015.

 

ABREU, PAULA A. ; SOUSA, THICIANA S. ; JIMENEZ, PAULA C. ; Wilke, Diego V. ; ROCHA, DANILO D. ; FREITAS, HOZANA P. S. ; PESSOA, OTÍLIA D. L. ; LA CLAIR, JAMES J. ; Costa-Lotufo, Letícia V. . Identification of Pyrroloformamide as a Cytokinesis Modulator. ChemBioChem (Print), v. x, p. n/a-n/a, 2014.

 

GUIMARÃES, LARISSA ; JIMENEZ, PAULA ; SOUSA, THICIANA ; FREITAS, HOZANA ; ROCHA, DANILO ; WILKE, D. V. ; MARTÍN, JESÚS ; REYES, FERNANDO ; DEUSDÊNIA LOIOLA PESSOA, OTÍLIA ; COSTA-LOTUFO, L. V. . Chromomycin A2 Induces Autophagy in Melanoma Cells. Marine Drugs, v. 12, p. 5839-5855, 2014.

 

TRINDADE-SILVA, A. E. ; RUA, C. P. J. ; ANDRADE, B. G. N. ; Vicente, A. C. P. ; SILVA, G. G. Z. ; BERLINCK, R. G. S. ; THOMPSON, F. L. . Polyketide Synthase Gene Diversity within the Microbiome of the Sponge Arenosclera brasiliensis, Endemic to the Southern Atlantic Ocean. Applied and Environmental Microbiology (Print), v. 79, p. 1598-1605, 2013.

 

Elshahawi, S., A. Trinidade-Silva, A. Hanora, A. Han, M. Flores, V. Vizzoni, C. Schrago, C.A. Soares,G.P. Concepcion, D. Distel, E. Schmidt, and M.G. Haygood. 2013. A boronated tartrolon antibiotic produced by symbiotic cellulose-degrading bacteria in shipworm gills. PNAS, January 22, 2013 vol. 110 no. 4 E295-E304. 10.1073/pnas.1213892110 http://www.pnas.org/content/110/4/E295.long

 

JIMENEZ, Paula Christine ; Wilke, Diego Veras ; Ferreira, Elthon Gois ; Takeara, Renata ; de Moraes, Manoel Odorico ; da Silveira, Edilberto Rocha ; da Cruz Lotufo, Tito Monteiro ; LOPES, Norberto Peporine ; Costa-Lotufo, Leticia Veras . Structure Elucidation and Anticancer Activity of 7-Oxostaurosporine Derivatives from the Brazilian Endemic Tunicate Eudistoma vannamei. Marine Drugs, v. 10, p. 1092-1102, 2012.

 

Trindade-Silva, Amaro E. ; Rua, Cintia ; Silva, Genivaldo G. Z. ; Dutilh, Bas E. ; Moreira, Ana Paula B. ; Edwards, Robert A. ; Hajdu, Eduardo ; Lobo-Hajdu, Gisele ; Vasconcelos, Ana Tereza ; Berlinck, Roberto G. S. ; Thompson, Fabiano L. . Taxonomic and Functional Microbial Signatures of the Endemic Marine Sponge Arenosclera brasiliensis. Plos One, v. 7, p. e39905, 2012.

 

FERREIRA, E. G. ; WILKE, D. V. ; JIMENEZ, Paula Christine ; OLIVEIRA, J. R. ; PESSOA, O D L ; SILVEIRA, Edilberto R ; VIANA, F. A. ; PESSOA, C. ; Moraes, Manoel Odorico ; HAJDU, Eduardo ; COSTA-LOTUFO, L. V. . Guanidine alkaloids from Monanchora arbuscula: chemistry and antitumor potential. Chemistry & Biodiversity (Print), v. 8, p. 1433, 2011.

 

Wilke, Diego Veras ; JIMENEZ, Paula Christine ; Araújo, Renata Mendonça ; da Silva, Wildson Max Barbosa ; Pessoa, Otília Deusdênia Loiola ; Silveira, Edilberto Rocha ; PESSOA, Claudia ; de Moraes, Manoel Odorico ; Skwarczynski, Mariusz ; Simerska, Pavla ; Toth, I. ; Costa-Lotufo, Letícia Veras . Pro-apoptotic activity of lipidic alpha-amino acids isolated from Protopalythoa variabilis. Bioorganic & Medicinal Chemistry (Print), v. 18, p. 7997-8004, 2010.

 

Trindade-Silva, Amaro E ; Lim-Fong, Grace E ; Sharp, Koty H ; Haygood, Margo G . Bryostatins: biological context and biotechnological prospects. Current Opinion in Biotechnology, p. online-online, 2010.

 

Yang, J. C. Madupu R. Durkin, A. S. Ekborg, N. A. Pedamallu, C. S. Hostetler, J. B. Radune, D. Toms, B. S. Henrissat, B. Coutinho, P. M. Schwarz, S. Field, L. TRINDADE-SILVA, A. E. SOARES, C. A. G. Elshahawi, S. Hanora, A SCHMIDT, E. W. Haygood, M. G. Posfai, J. Benner, J. Madinger, C. Nove, J. Anton, B. Chaudhary, K. Foster, J. ,  et al. ; The Complete Genome of Teredinibacter turnerae T7901: An Intracellular Endosymbiont of Marine Wood-Boring Bivalves (Shipworms). Plos One, v. 4, p. e6085, 2009. 

 

WILKE, D. V. ; JIMENEZ, Paula Christine ; PESSOA, Claudia ; MORAES, Manoel Odorico de ; ARAUJO, R. M. ; SILVA, W. M. B. ; SILVEIRA, Edilberto R ; PESSOA, O D L ; BRAZFILHO, Raimundo ; LOPES, Norberto Peporine ; Costa-LOTUFO, L. V. . Cytotoxic lipidic alpha-amino acids from the zoanthid Protopalythoa variabilis from the northeastern coast of Brazil. Journal of the Brazilian Chemical Society (Impresso), v. 20, p. 1455-1459, 2009.

 

COSTA-LOTUFO, L. V. ; WILKE, D. V. ; JIMENEZ, Paula Christine ; EPIFÂNIO, R. A. . Organismos marinhos como fonte de novos fármacos: histórico e perspectivas. Química Nova (Impresso), v. 32, p. 703-716, 2009.

 

TAKEARA, R ; JIMENEZ, Paula Christine ; WILKE, D. V. ; MORAES, Manoel Odorico de ; PESSOA, C. ; LOPES, Norberto Peporine ; LOPES, J. L. C. ; LOTUFO, T. M. C. ; COSTA-LOTUFO, L. V. . Antileukemic effects of Didemnum psammatodes (Tunicata: Ascidiacea) constituents. Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, v. 151, p. 363-369, 2008. 

 

JIMENEZ, Paula Christine ; WILKE, D. V. ; TAKEARA, R ; LOTUFO, T. M. C. ; PESSOA, C. ; MORAES, Manoel Odorico de ; LOPES, Norberto Peporine ; COSTA-LOTUFO, L. V. . Cytotoxic activity of a dichloromethane extract and fractions obtained from Eudistoma vannamei (Tunicata: Ascidiacea).. Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, v. 151, p. 391-398, 2008.